Another mode of action in testosterone optimization is the use of aromatase inhibitors. Circulating estrogens in the body can be decreased by inhibition of their biosynthesis from testosterone. The metabolic target of estrogen synthesis inhibition is aromatase enzymes. Aromatase enzymes are part of the body s biochemistry system that are used in the conversion of testosterone to estrogen. So, when aromatase enzyme activity is inhibited (blocked), this prevents conversion of testosterone into estrogen. For this central role in the production of estrogen, aromatase has become a central enzyme target of inhibition for people who want to optimize their testosterone levels and minimize estrogen levels.
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